The circular economy (CE) has emerged as a paradigm to protect the environment and the well-being of future generations. In parallel, Blockchain technology (BC) has emerged as a critical enabler for accelerating the transition toward a CE. In order to understand and summarize prior research on the role of BC in the CE, we conducted a systematic literature review (SLR) of 70 seminal articles published before July 2022. Six main themes emerged: a) CE approaches and practices, b) BC and the integration of the Internet of Things (IoT), c) sustainable supply chain management, d) BC and the CE in the COVID-19 era, e) sector-specific BC applications, and f) barriers to BC adoption in the CE. Furthermore, we develop a comprehensive framework that integrates stakeholders, strategies and practices, industrial sectors and a BC-enabled CE.